Bone Regeneration

In the past, the treatment of periodontal (gum) disease was considered to be painful and disfiguring. For many years, the best way to achieve the ultimate goal of therapy (shallow, maintainable pockets) was to do resective surgical procedures that often resulted in the exposure of sensitive root surfaces and the appearance of "long" teeth.

Today, periodontists are often able to restore or regenerate missing bone and attachment around teeth subjected to long-standing periodontal disease. In addition, if you have lost a tooth due to trauma or disease, we can restore or regenerate bone prior to the placement of bridges or implants.

Guided Tissue Regeneration (GTR) refers to procedures that attempt to regenerate lost periodontal structures (bone, periodontal ligament, and connective tissue attachment) that support our teeth. This is accomplished using biocompatible membranes, often in combination with bone grafts and/or tissue stimulating proteins.

Guided Bone Regeneration (GBR) refers to procedures that attempt to regenerate bone prior to the placement of bridges or, more commonly, implants. This is accomplished using bone grafts and biocompatible membranes that keep out tissue and allow the bone to grow.

Remember, not every case is suitable for grafting so ask your dentist or Dr.'s Aldredge or Nejat if this procedure can benefit you.

Correction of
bone defects (around teeth)
The procedure consists
of filling up the defect or
cavity in the bone with a
biocompatible material
providing a protected
environment for regeneration.

Why Bone Grafting (for dental implants)?

In many instances, a potential implant site in the upper or lower jaw does not offer enough bone volume or quantity to accommodate a dental implant of proper size or in the proper place. This is usually a result of bone resorption that has taken place since one or more teeth (if not all) were lost. Bone Grafting or Guided Bone Regeneration -GBR procedures usually try to re-establish bone dimension, which was lost due to resorption. A bone graft normally takes at least four to six months to heal, before a dental implant can be placed into it. There are times also that multiple grafts may be needed to produce the amount of bone needed. This is dependant on a persons health and amount of bone being grafted.

Years ago the lack of bone posed a considerable problem and sometimes implant placement was impossible because of that. Today, however, we have the ability to grow bone where needed. This not only gives us the opportunity to place implants of proper length and width , it also gives us a chance to restore the esthetic appearance and functionality better.

Click below to view each complication of tooth loss

Effects of Wearing Dentures

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Different Types of Bone Grafting Procedures

Maxillary Sinus Augmentation / Lift
Socket Preservation
Guided Bone Regeneration / GBR (Ridge Augmentation & Jaw Reconstruction)
Grafting Materials

Maxillary Sinus Augmentations:

One of the most frequently applied grafting procedures is the Sinus Augmentation. This procedure is restricted only to the upper jaw.

As we get older our sinuses grow larger in volume and literally take away valuable bone from the jaw ridge as shown below on the x-rays. This is not a pathological condition, on the very contrary, it happens to almost every one. This process is called Pneumatization of the Para-nasal sinuses. Click here to see consequences of sinus expansion

Once teeth are lost in that particular area it makes it difficult if not impossible to place endosseous implants in that area, as you can see on the right image above. For this particular problem a grafting method was developed to literally raise the bottom of the sinus back up, graft bone underneath and, thus, create enough space for one or more dental implants. Compare the two x-rays below.

This procedure has been performed successfully for over two decades now and is considered an accepted and predictable method of bone grafting. The grafting material being used can be of either of the above mentioned categories. Again autogenous bone will give you the best and fastest results. However it would take a considerable volume of bone (5cc to 10cc per side) to perform a typical sinus augmentation; usually more than can be harvested form intra-oral donor sites. Therefore, we sometimes downsize to an allograft, alloplast or xenograft or a combination (sometimes mixed with a little autograft) and take into account a longer maturation time. An autograft takes approximately 4 to 6 months to mature in the sinus, an allograft, alloplast or xenograft may take 9 months or more.

Sinus Augmentations and implant placement can sometimes be performed as a single procedure, if enough bone between the upper jaw ridge and the bottom of the sinus is available to stabilize the implant well. If not enough bone is available, the Sinus Augmentation will have to be performed first, then the graft will have to mature for several months (depending on the graft material used). Once the graft has matured the implants can be placed.

The Autograft is considered the Gold Standard. It is defined as tissue transplanted from one site to another within the same individual. It is basically your very own bone taken from a donor site and placed somewhere else in the body, into the recipient site. The best success rates in bone grafting have been achieved with autografts, because these are essentially living tissues with their cells intact. There is no immune reaction and the microscopic architecture is perfectly matched. The only disadvantage of the autograft is that it has to be harvested from a secondary site in your body, which usually means more morbidity and a more complicated surgery, overall. For most grafting purposes confined to Oral Implantology we can use another part of the jaw (i.e., chin or back portions of jaw) as an acceptable donor site. This way, we stay surgically inside the mouth and avoid any extraoral wounds and scarring. Sometimes, however, when there is not enough bone volume available intraorally, we have to get bone from other parts of the body (usually your hip bone or your tibia (shin) bone) or even from a bottle - alloplast, allograft, or xenograft.

The Allograft is defined as a tissue graft between individuals of the same species (i.e., humans) but of non-identical genetic composition. The source is usually cadaver bone, which is available in large amounts. This bone however has to undergo many different treatment sequences in order to render it neutral to immune reactions and to avoid cross contamination of host diseases. These treatments may include irradiation, freeze-drying, acid washing and other chemical treatments. In the U.S. virtually all donors are being prescreened for infectious diseases before their bone is even accepted into the tissue banks. After that the processing of the bone would eliminate virtually any chance of cross-infection.

The Xenograft is defined as a tissue graft between two different species (i.e. bone of bovine origin). Tissue banks usually choose these graft materials, because it is possible to extract larger amounts of bone with a specific microstructure (which is an important factor for bone growth) as compared to bone from human origin.

The Alloplast usually includes any synthetically derived graft material not (coming) from animal or human origin. In Oral Implantology this usually includes Hydroxyapatite or any formulation thereof.

Each of the bone graft materials is usually developed with a specific purpose or advantage in mind. Some claims made by tissue banks about a certain bone graft material may sometimes have to be taken with a grain of salt, until independent research can verify those claims. The main purpose of using the latter four of the above graft materials is usually to avoid a secondary surgery for harvesting autogenous bone. Your surgeon will make a decision with respect to the bone graft material, based on your individual needs and the latest research in that field.

BONE GRAFT
BEFORE		AFTER